NMNAT1 anticorps (AA 229-279)

N° du produit ABIN7454578

L’anticorps Lapin Polyclonal anti-NMNAT1 a été validé pour WB et IHC (fp). Il convient pour détecter NMNAT1 dans des échantillons de Humain et Souris.

Aperçu rapide pour NMNAT1 anticorps (AA 229-279) (ABIN7454578)

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMNAT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-NMNAT1 anticorps

Épitope: AA 229-279

Fonction: Rabbit anti-NMNAT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 229 and 279

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NMNAT1

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Autre désignation: NMNAT1

Sujet: Background: Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. NMNAT1 is an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. NMNAT1 is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown NMNAT1 can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecul [taken from NCBI Entrez Gene (Gene ID: 64802)].

ID gène: 64802

NCBI Accession: NP_073624

UniProt: Q9HAN9